Lexiphone was first organized in France in the mid-1970s by Dr. Isi Beller, a psychiatrist and Professor of Psychology in Paris. Dr. Beller has spent more than thirty years researching dyslexia and, in the course of that research, he developed (invented) a treatment method for dyslexia. He received a patent on his treatment invention in France in 1984 and in the United States in 1987. He then received an additional patent in France in 1992 and in Europe and the United States in 1993. In 1996 he was awarded an international patent on his treatment invention.

In the mid-1980s Dr. Beller licensed his treatment method (Lexiphone) for a territory which included all of Western Europe. The Lexiphone treatment has been in use in France, Belgium and Switzerland for more than fifteen years. More than 20,000 patients have been treated with the Lexiphone method.

In 1996, Dr. Beller was introduced to Frederick Wrightson (American) by a mutual friend, Jean-Pierre Mahot. Both Messrs. Wrightson and Mahot had daughters who suffered from dyslexia. Mr. Wrightson contacted the headmasters at two New England schools (that his daughter had attended), which specialized in educating children with learning disabilities and discussed the Lexiphone treatment method. After reading material on Lexiphone both headmasters expressed great interest in the treatment method. Mr. Wrightson then asked Dr. Beller to travel to the US for a meeting with one of the headmasters. This meeting resulted in an introduction to Dr. John Locke at the MGH Institute of Health Professions at Massachusetts General Hospital, which in turn led to the formation of Lexiphone (U.S), Inc. (recently renamed Lexiphone Technology Corporation) and a large efficacy study of the Lexiphone treatment by MGH and the University of Sheffield (UK). This study has been completed.

Lexiphone Technology Corporation intends to introduce the Lexiphone treatment in the US.